Sappani Foundation created a worm avatar for drug repurposing in 2019. After many twists and turns, HMG-CoA reductase emerged as a target that may restore the balance between polyprenol and dolichol.
One of my concerns with them is that they might increase Glycanage, b/c N-linked glycosylation is important for the initial steps in forming more complex glycans
you may also want to supply bile acids in addition to cholesterol when try statin. Good luck
One of my concerns with them is that they might increase Glycanage, b/c N-linked glycosylation is important for the initial steps in forming more complex glycans
https://www.rapamycin.news/t/statins-often-used-to-reduce-rapamycin-increased-ldl-inhibit-coenzyme-q10-and-ggp-mk4-and-dolichol-and-n-linked-glycosylation-other-negative-effects/13775/9