Collagen is a slippery eel. After trying and failing to visualize collagen inside PLOD1-kEDS fibroblasts, we pivoted to measuring collagen secreted by cells as a readout for a drug repurposing screen.
Unexpected PLOD1 twist
Unexpected PLOD1 twist
Unexpected PLOD1 twist
Collagen is a slippery eel. After trying and failing to visualize collagen inside PLOD1-kEDS fibroblasts, we pivoted to measuring collagen secreted by cells as a readout for a drug repurposing screen.